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Institute for Human Neuroscience

 

MRI and brain scans

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The Institute for Human Neuroscience at Boys Town National Research Hospital is revolutionizing child and adolescent brain research. Located on Boys Town campus in Omaha, Nebraska, it is one of the most cutting-edge neuroscience research facilities in the nation and the only site in the world with two next-generation MEG (magnetoencephalography) systems. The Institute for Human Neuroscience is home to the Center for Pediatric Brain Health, an NIH Center for Biomedical Research Excellence which focuses on advancing and expanding pediatric neuroimaging research.

The Institute's research on pediatric brain health is critical, as it will help define normal brain development in children and enable investigators to understand how the brain changes as kids move through puberty and into young adulthood, which is obviously a period of major cognitive and emotional change. Once the parameters of typical brain development are better understood, the team will be able to identify the impact of traumatic experiences on brain development, as well as the brain changes associated with the emergence of anxiety disorders, depression, and other conditions. Without a deep understanding of healthy brain development, it is exceedingly difficult to develop new types of therapies for these neurodevelopmental disorders.

The Institute for Human Neuroscience is setting the pace for neuroscience research, especially regarding pediatric neuroimaging and developmental neuroscience. Having the Institute directly on the Boys Town campus means the research findings can be directly used to improve treatments and help change the way America cares for children and families, everywhere.

What is a MEG?

MEG (magnetoencephalography) technology uses very sensitive magnetic sensors that are configured within a helmet to measure human brain function. The technology is noninvasive and totally silent, and unique in that it can measure what is happening in the brain at a millisecond level. This high temporal precision allows researchers to image the brain as cognition evolves, thereby allowing dynamic maps of neural activity to be created.

What is fMRI?

fMRI (functional magnetic resonance imaging) is a novel method that allows a high-performance MRI system to be used to measure brain function with high spatial precision. MRI is typically used to measure brain structure. Investigators in the Institute for Human Neuroscience often combine MEG imaging with both fMRI and structural MRI (i.e., multimodal imaging) to get the most advanced information on brain structure and function.

What is OPM?

OPM (optically-pumped magnetometry) is the first wearable MEG device that will allow researchers to study brain activity of small children and populations of individuals that have physical difficulty sitting still. This state-of-the-art equipment allows scientists, for the first time, to study how brain structure affects brain function and that development through the first few months of human life.​ Including identifying patterns of certain medical conditions within the brain of young children.

 

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