Much of the hospital's success in identifying and treating children with hearing loss is the result of the rapid transfer of research findings from laboratories to clinic and bedside.

Areas of Research

Barbara J. Morley
Curriculum Vita

Personal Information:

Address: Boys Town Nat'l Research Hospital (BTNRH), 555 N. 30th St., Omaha, NE 68131
Phone: 402-498-6584 (voice); 402-498-6351 (fax)
Email:morley@boystown.org

Education:

June 1968	B.A., Psychology/Humanities, MacMurray College, Jacksonville, IL
Apr. 1973	Ph.D., Bio-Psychology, University of Maine, Orono, ME

Professional Experience:

1980-	Scientific Director, Neurochemistry Laboratory and Support Facilities, BTNRH, Omaha, NE
1985-	Professor, Dept. of Biochemistry, Creighton Univ. School of Medicine, and Dept. of Pharmacology, Univ. of Nebraska, Omaha, NE
1985-02	Professor, Dept. Otolaryngology & Human Communication, Creighton Univ. School of Medicine, Omaha, NE
1993	Sabbatical leave, Molecular Biology, Baylor University, Houston, TX
1985-86	Sabbatical leave, Molecular Biology, Salk Institute, San Diego, CA
1980-85	Associate Professor, Creighton Univ. School of Medicine, and the Graduate School of the Univ. of Nebraska, Omaha, NE
1980-85	Associate Professor, Creighton Univ. School of Medicine, and the Graduate School of the Univ. of Nebraska, Omaha, NE
1978-80	Assistant Professor, Neurosciences Program, Univ. of Alabama Medical School, Birmingham, AL
1976-78	NIMH Postdoctoral Fellow, Neurosciences Program,Univ. of Alabama Medical School, Birmingham, AL
1973-76	Assistant Professor, William Paterson College, Wayne, NJ
1973	Assistant Professor, Univ. of Maine, Orono, ME
1972-73	Research Associate, Univ. of Maine, Orono, ME
1971-72	Instructor, Univ. of Maine, Orono, ME

Professional Activities and Memberships:

• Memberships: Society for Neuroscience, New York Academy of Science, American Association for the Advancement of Science, Psi Chi, Phi Kappa Phi, Sigma Xi, President, Midlands Chapter of the Society for Neuroscience.
  
• Review panel member: Sensory Systems, National Science Foundation; Integrative, Functional, and Cognitive Neuroscience (IFCN-6) Study Section, National Institutes of Health; Neuroscience & Nicotine Dependence, California Tobacco-Related Disease Research Program; Arizona Mental Health Initiative.
  
• Reviewer for: Brain Research, Physiology & Behavior, J. Biological Chemistry, Neuroscience & Biobehavioral Reviews, Life Sciences, J. Neurochemistry, Brain Research Bulletin, Pharmacology, Biochemistry & Behavior, Experimental Brain Research, Analytical Chemistry, Molecular Pharmacology, Molecular Neurobiology, Journal of Neuroscience, Hearing Research, J. Auditory Neuroscience, Pharmacol. Review, J. Assoc. Res. Otol. (JARO), J. Chem. Anat.

Publications:

Morley, B.J. (1972). Experimental mammalian behavioral genetics: Single gene effects and behavor. Univ. of Maine, Orono, ME.

Abelson, R.M., Morley, B.J. & Cannon, R.J. (1973). Selection for an instrumental response -- escape from noise. J. Audit. Res. 13, 152-157.

Morley, B.J. & Abelson, R.M. (1974). High-intensity ultrasonic sound: A better rat. A reply to Pinel (1972). Psychol. Reports 35, 152-154.

Morley, B.J. & Abelson, R.M. (1974). The presence of neurofibrillary inclusions in the nucleus of the trapezoid body of the rat. J. Audit. Res. 14, 208-211.

Morley, B.J. & Abelson, R.M. (1975). Further comments on the deleterious behavioral and physiological effects of sound. Psychol. Reports 37, 544-546.

Morley, B.J., Cohen, S.L. & Poplawsky, A. (1977). The differential effects of a high-carbohydrate diet on the behavior of male and female rats. Neurosci. Lett. 7, 347-352.

Morley, B. & Bradley, R.J. (1977). Spectral analysis of mouse EEG after the administration of N,N-dimethyltryptamine. Biol. Psych. 12, 757-769.

Morley, B.J., Abelson, R.M. & Cannon, R.J. (1977). Escape from electrical stimulation on the trapezoid body in rats bred for escape from noise. Physiol. Behav. 18, 35-39.

Morley, B.J., Lorden, J.F., Brown, G.B., Kemp, G.W. & Bradley, R.J. (1977). Regional distribution of nicotinic acetylcholine receptors in rat brain. Brain Res. 134, 161-166.

Morley, B.J., Robinson, G.R., Brown, G.B., Kemp, G.E. & Bradley, R.J. (1977). The effects of dietary choline on nicotinic AChR in brain. Nature 266, 848-849.

Russin, R. & Morley, B.J. (1978). Species-specific responses in the extinction of water- and food-motivated behaviors. Physiol. Behav. 21, 835-837.

Morley, B.J. & Worsham, E. (1978). The effects of scopolamine and physostigmine on the activity of isolated and socially reared rats. Physiol. Psych. 6, 83-88.

Morley, B.J. & Russin, R. (1978). The effects of scopolamine on extinction and spontaneous recovery. Psychopharmacol. 56, 301-304.

Bradley, R.J., Dwyer, D., Morley, B.J., Robinson, G., Kemp, G.E. & Oh, S.H. (1978). Humoral immunity in myasthenia gravis: Relationship to disease severity and steroid treatment. Lancet, June 24.

Bradley, R.J., Dwyer, D., Morley, B.J., Robinson, G., Kemp, G.E. & Oh, S.H. (1979). Humoral immunity in myasthenia gravis: Relationship to disease severity and steroid treatment. In S. Tucek (Ed.), Progress in Brain Research: The Cholinergic Synapse, pp 441-448.

Morley, B.J., Kemp, G.E. & Salvaterra, P.M. (1979). a-bungarotoxin binding in the CNS. Life Sciences 24, 859-872.

Bradley, R.J., Morley, B.J., Barker, S.A. & Smythies, J.R. (1979). Hallucinogens. In: Handbook of Clinical Neurology. North-Holland Publ. Co., Amsterdam, pp 329-346.

Kemp, G.E., Morley, B.J., Dwyer, D. & Bradley, R.J. (1980). Purification and partial characterization of nicotinic acetylcholine receptors from normal and denervated muscle. Memb. Biochem. 3, 229-249.

Snead, O.C., Benton, J.W., Dwyer, D., Morley, B.J., Kemp, G.E., Bradley, R.J. & Oh, S.J. (1980). Juvenile myasthenia gravis. Neurology 30, 732-739.

Morley, B.J. (1981). The properties of brain nicotine receptors. Pharmacol. Ther. 15, 111-122.

Morley, B.J. & Kemp, G.E. (1981). Characterization of a putative nicotinic acetylcholine receptor in mammalian brain. Brain Res. Rev. 217, 81-104.

Snead, O.C. & Morley, B.J. (1981). Ontogeny of gamma-hydroxybutyric acid. I: Regional con­centration in developing rat, monkey, and human brain. Develop. Brain Res. 1, 579-589.

Cohen, S.L., Morley, B.J. & Snead, O.C. (1981). An EEG analysis of convulsive activity pro­duced by cholinergic agents. Prog. Neuro-Psychopharmacol. 5, 383-388.

Morley, B.J., Dwyer, D.S., Strang-Brown, P.F., Bradley, R.J. & Kemp, G.E. (1982). Evidence that certain peripheral anti-acetylcholine receptor antibodies do not interact with brain BuTX sites. Brain Res. 262, 109-116.

Morley BJ, Rodriguez-Sierra JF, Clough RW. (1983). Increase in hypothalamic nicotinic acetylcholine receptors in prepuberal female rats administered estrogen. Brain Res. 278, 262-265.

Farley, G.R., Morley, B.J., Javel, E. & Gorga, M.P. (1983). Single-unit responses in rat inferior colliculus during iontophoresis of cholinergic agents. Hearing Res. 11, 73-91.

Morley, B.J., Farley, G.R. & Javel, E. (1983). Nicotinic acetylcholine receptors in mammalian brain. Trends Pharmacol. Sci. 4, 225-227.

Morley, B.J., Farley, G.R. & Javel, E. (1984). Nicotinic acetylcholine receptors in mammalian brain. In: Receptors, Again. Elsevier/North-Holland Publ. Co., Amsterdam, pp 154-159.

Morley, B.J. (1984). The properties of brain nicotine receptors. In D.K. Balfour (Ed.), Nicotine and the Tobacco-Smoking Habit.

Morley, B.J. (1985). The localization and origin of somatostatin-containing fibers in an auditory brainstem nucleus. Peptides 6, 165-172.

Rodriguez-Sierra, J. & Morley, B.J. (1985). Evidence that cell bodies in the arcuate nucleus of the hypothalamus are not cholinergic. Neuroendocrinol. 41, 427-431.

Morley, B.J., Farley, G.R. & Javel, E. (1985). Putative neurotransmitter receptors in the central auditory system. In D. Drescher (Ed.), Auditory Biochemistry. C.C. Thomas, Springfield, pp. 227-243.

Morley, B.J., Spangler, K. & Javel, E. (1985). The development of somatostatin in the inter­peduncular nucleus of the cat. Dev. Brain Res. 20, 241-248.

Kemp, G., Bentley, L., McNamee, M.G. & Morley, B.J. (1985). Purification and charac­terization of the a-bungarotoxin binding protein from rat brain. Brain Res. 374, 274-283.

Kemp, G.E. & Morley, B.J. (1986). Ganglionic nAChRs and high-affinity nicotinic binding sites are not equivalent. FEBS Lett. 205, 265-268.

Morley, B.J. & Garner, L.L. (1986). Increases in the concentration of brain a-bungarotoxin binding sites induced by dietary choline are age-dependent. Brain Res. 378, 315-319.

Morley, B.J. (1986). The interpeduncular nucleus: a center for neurochemical integration. Int'l Rev. Neurobiol. 28, 157-182.

Morley, B.J. & Garner, L.L. (1987). Increases in the concentration of brain nicotinic receptors by dietary choline. In R.J. Wurtman, S.H. Corkin & J.H. Growdon (Eds.), Proceed. 4th Mtg., Int'l Study Group on Pharmacology of Memory Disorders Associated with Aging. Ctr. for Brain Sciences & Metabolism Charitable Trust, Cambridge, MA, 449-498.

Morley, B.J. & Fleck, D. (1987). A time-course and dose-response study of the regulation of brain nicotinic receptors by dietary choline. Brain Res. 421, 21-29.

Spangler, K.M. & Morley, B.J. (1987). Somatostatin-immunoreactivity in the midbrain of the cat. J. Comp. Neurol. 260, 87-97.

Whiting, P.J., Liu, R., Esch, F., Morley, B.J. & Lindstrom, J.M. (1987). Structurally different neuronal nicotinic acetylcholine receptor subtypes purified and characterized using mono­clonal antibodies. J. Neurosci. 7, 4005-4016.

Morley, B.J., Fuxe, K., Holmstedt, B. & Sundwall, A. (1989). a-bungarotoxin receptors in the CNS. In A. Nordberg et al. (Eds.), Progress in Brain Res. New York: Elsevier Science Publ., pp 101-108.

Morley, B.J. & Murrin, L.C. (1989). AF64 depletes hypothalamic high-affinity choline uptake and disrupts the circadian rhythm of locomotor activity without altering the density of nicotinic acetylcholine receptors. Brain Res. 504, 238-246.

Rodriguez-Sierra, J.F., Burns, S.P., Earl, R.A., Schneider, B.L. & Morley, B.J. (1990). Infant rat exposure to aspartate and glutamate: Neuroendocrinopathies and structural analysis of brain damage. In G. Lubec (Ed.), Amino Acids. Pergammon Press, NY, pp 529-537.

Morley, B.J. & Garner, L.L. (1990). AF64A depletes hippocampal high affinity choline uptake but does not alter the density of a-bungarotoxin binding sites or modify the effect of exo­genous choline. Brain Res. 515, 1-5.

Morley, B.J. & Garner, L.L. (1990). Light-dark variation in response to chronic nicotine treatment & the density of hypothalamic a-bungarotoxin receptors. Pharmacol. Biochem. Behav. 37, 239-245.

Morley, B.J., Spangler, K.M., Schneider, B. & Javel, E. (1991). Selective degeneration of a putative cholinergic pathway in the chinchilla cochlea by ethylcholine aziridinium ion. Brain Res. 544, 94-100.

Rosa-Molinar, E., Rodriguez-Sierra, J.F., Schneider, B.L. & Morley, B.J. (1992). Surface layer cytoarchitecture of an epimorphic regenerated hormonally-induced gonopodium in the female mosquitofish, Gambusia affinis affinis as revealed by scanning electron microscopy. Anat. Rec.

Weekly, J.M., Warr, W.B. & Morley, B.J. (1992). Distribution of olivocochlear neurons in the chinchilla. Soc. Neurosci. Abstr. 18, 1192.

Morley, B.J. & Murphy, R. (1993). Effects of neonatal thymectomy on the densities of nicotnic cholinergic receptors in skeletal muscle and brain. Exp. Neurol. 120, 277-282.

Drescher, D.G., Green, G.E., Khan, K.M., Hajela, K., Beisel, K.W., Morley, B.J. & Gupta, A.K. (1993). Analysis of g-aminobutyric acid A receptor subunits in the mouse cochlea by means of the polymerase chain reaction. J. Neurochem. 61, 1167-1170.

Roll, R.L., Jones, T.A., Benowitz, N.L. & Morley, B.J. (1993). The chronic infusion of nicotine into the developing chick embryo does not alter the density of [ 3H]nicotine-binding sites or vestibular function. Brain Res. 604, 260-265.

Li, H.-S., Niedzielski, A.S., Beisel, K.W., Hiel, H., Wenthold, R.J. & Morley, B.J. (1994). Identification of a glutamate/aspartate transporter in the rat cochlea. Hearing Res. 78, 235-242.

Smith, D.D., Conlon, J.M., Petzel, J., Chen, L., Murphy, R.F. & Morley, B.J. (1994). Solid-phase peptide synthesis and biological activity of bovine thymopoietin II (bTP-II). Peptides 44, 183-191.

Drescher, D.G., Khan, K.M., Green, G.E., Morley, B.J., Beisel, K.W., Kaul, J., Gordon, D., Gupta, A.K., Drescher, M.J. & Barretto, R.L. (1996). Analysis of nicotinic acetylcholine receptor subunits in the cochlea of the mouse J. Comp. Biochem. Physiol.112C, 267-273.

Hiel, H., Happe, H.K., Warr, W.B. & Morley, B.J. (1996). The regional distribution of a creatine transporter in rat auditory brainstem: An in situ hybridization study. Hear. Res.98, 29-37.

Hiel, H., Elgoyhen, A.B., Drescher, D.G. & Morley, B.J. (1996). Expression of nicotinic acetylcholine receptor mRNA in the adult rat peripheral vestibular system. Brain Res. 738, 347-352.

Morley, B.J. (1997). The embryonic and post-natal expression of the nicotinic receptor a3-subunit in rat lower brainstem. Mol. Brain Res. 48, 407-412.

Happe, H.K. & Morley, B.J. (1998). Nicotinic acetylcholine receptors in rat cochlear nucleus: [ 125I]- a -bungarotoxin receptor autoradiography and in situ hybridization of a 7 nAChR subunit mRNA. J. Comp. Neurol. 397, 163-180.

Morley, B.J. (1998). ARIA is heavily expressed in rat peripheral auditory and vestibular ganglia. Mol. Brain Res. 54, 170-174.

Morley, B.J., Li, H., Hiel, H., Drescher, D.G. & Elgoyhen, A.B. (1998). Identification of the subunits of the nicotinic cholinergic receptors in the rat cochlea using RT-PCR and in situ hybridization. Mol. Brain Res. 53, 78-87.

Simmons, D.D. & Morley, B.J. (1998). Differential expression of the a9 nicotinic acetylcholine receptor subunit in neonatal and adult cochlear hair cells. Mol. Brain Res. 56, 287-292.

Azeredo, W.J., Kliment, M.L., Morley, B.J., Relkin, E., Slepecky, N.B., Sterns, A., Warr, W.B., Weekly, J.M. & Woods, C.I. (1999). Olivocochlear neurons in the chinchilla: A retrograde fluorescent labeling study. Hear. Res. 134, 57-70.

Morley, B.J. & Happe, H.K. (2000). Cholinergic receptors: Dual roles in transduction and plasticity. Hear. Res. 147, 104-112.

Morley, B.J. and Simmons, D.D. (2002). Developmental mRNA expression of the a10 nicotinic acetylcholine receptor subunit in the rat cochlea. Devel. Brain Res. 129, 87-96.

Morley, B.J., Warr, W.B. & Rodriguez-Sierra, J.F. (2004). Transient expression of acetylcholinesterase in the posterior ventral cochlear nucleus of rat brain. J. Assoc. Res. Otolaryngol.5, 391-403.

Happe, H.K. & Morley, B.J. (2004). α7 nicotinic acetylcholine receptors in the lower auditory brainstem. Mol. Brain Res. 153, 29-37.

Morley, B.J. & Rodriguez-Sierra, J.F. (2004). A phenotype for the α7 nicotinic acetylcholine receptor null mutant. Brain Res.1023, 41-47.

Papers and Abstracts:

Morley, B.J. & Abelson, R.M. (1971). The effects of chlorpromazine on escape responding. Pre­sented to Eastern Psychol. Assoc., New York.

Morley, B.J. & Abelson, R.M. (1973). The effects of noise escape training on the cells of the nucleus of the trapezoid body: A light and electron microscopic investigation. Presented to Am. Psychol. Assoc., Montreal, Canada.

Cannon, T.J., Abelson, R.M. & Morley, B.J. (1974). Permanent enhancement of escape from noise by a single intersession interval. Presented to Eastern Psychol. Assoc.

Cannon, T., Abelson, R.M. & Morley, B.J. (1975). Decreased escape from both foot-shock and in­tense white noise produced by parachlorophenylalanine. Presented to East. Psychol. Assoc.

Morley, B.J., Cohen, S.L. & Poplawski, A. (1976). Sex differences in behavior following rearing on a high-carbohydrate diet. Soc. Neurosci. Abs. 2, 853.

Morley, B.J. & Worsham, E. (1976). The long-term effects of PCA on activity and response to amphetamines. Presented to the Am. Psychol. Assoc. Washington, DC.

Morley, B.J. & Worsham, E. (1976). The effects of PCA on activity and variable-interval performance. Presented to the Southern Neurosci. Soc. Olive Branch, MS.

Cannon, T.J., Abelson, R.M. & Morley, B.J. (1976). An examination of the behavioral and ana­tomical relationships between startle and pinna reflexes. Presented to East. Psychol. Assoc.

Russin, R. & Morley, B.J. (1976). Partial reinforcement effects with food and water reward. Presented to the Southwestern Psychol. Assoc. Albuquerque, NM.

Morley, B.J. & Russin, R. (1976). Differential effects of scopolamine on responding during extinction and spontaneous recovery following training on fixed ratio schedules. Presented to S.E. Psychol. Assoc. New Orleans, LA.

Worsham, E., Morley, B.J. & DeJianne, D. (1976). The effects of social contact on avoidance and response to cholinergic drugs. Presented to S.E. Regional Assoc. Animal Behav. Soc.

Morley, B.J., Lorden. J.F., Brown, G.B., Kemp, G.E. & Bradley, R.J. (1977). Regional distribu­tion of nicotinic acetylcholine receptor in rat brain. Soc. Neurosci. Abs. 3, 458.

Bradley, R.J., Morley, B.J., Lorden, J.F., Brown, G.B. & Kemp, G.E. (1977). Regulation of nicotinic acetylcholine receptor in brain. Soc. Neurosci. Abs. 3, 453.

Morley, B.J. & Kemp, G.E. (1978). Developmental studies of a-bungarotoxin binding in mammalian brain. Soc. Neurosci. Abs. 4, 517.

Oh, S.J., Kemp, G.E., Dwyer, D., Morley, B.J., Robinson, G. & Bradley, R.J. (1978). Acetyl­choline antibody in relation to severity of myasthenia gravis. Presented at the IVth Int'l Congress on Neuromuscular Disease. Montreal, Canada.

Worsham, E., Morley, B.J. & Wallace, L. (1978). The effects of p-chloroamphetamine on the development of behavior and brain catecholamines. Soc. Neurosci. Abs.2, 859.

Snead, O.C. & B.J. Morley (1979). Ontogeny of gamma-hydroxybutyrate in human and rhesus monkey brain. Soc. Neurosci. Abs. 5, 416

Morley, B.J. & Kemp, G.E. (1979). Studies of the interaction of eel acetylcholine receptor anti­body with highly purified brain acetylcholine receptor. Soc. Neurosci. Abs. 5, 307.

Snead, O.C., Beaton, J.M., Dwyer, D., Morley, B.J., Kemp, G.E. & Bradley, R.J. (1979). Juvenile myasthenia gravis. Neurol. 29, 595.

Kemp, G.E., Furner, R. & Morley, B.J. (1980). Purification of a putative nicotinic acetylcholine receptor. Soc. Neurosci. Abs. 6, 210.

Morley, B.J. & Snead, O.C. (1980). Absence of immunoprecipitation of brain BuTX sites by anti-AChR antisera. Trans. Am. Soc. Neurochem. 11, 111.

Strang-Brown, P. & Morley, B.J. (1981) Evidence that anti-acetylcholine receptor antibodies do not interact with hypothalamic BuTX sites in vivo and in vitro. Soc. Neurosci. Abs. 7, 203.

Morley, B.J. & Koenig, J.J. (1982). Somatostatin-immunoreactivity in the brain stem: A com­parison of methods. Soc. Neurosci. Abs. 8, 113.

Morley, B.J. (1982). The distribution of somatostatin in sensory nuclei. Presented at 1st Int'l Mtg., Int'l Brain Res. Org. Lausanne, Switzerland.

Farley, G.R., Morley, B.J., Javel, E. & Gorga, M.P. (1982). Single-unit responses in rat inferior colliculus during iontophoresis of cholinergic agents. Soc. Neurosci. Abs. 8, 348.

Farley, G.R., Morley, B.J., Javel, E. & Gorga, M.P. (1982). Effects of cholinergic agents on single-unit responses in the rat inferior colliculus. J. Acoust. Soc. Am.

Rodriguez-Sierra, J., Morley, B.J. & Clough, R.W. (1982). Prepubertal exposure to estrogen in­creases the number of nicotinic receptors in the medio-basal hypothalamus (MBH) of the female rat. Soc. Neurosci. Abs. 8, 196.

Farley, G., Javel, E., Morley, B.J. & Goldgar, D. (1983). Physiological cell classes in the rat inferior colliculus examined by factor and cluster analytic techniques. Soc. Neurosci. Abs. 9, 214.

Morley, B.J. & Rodriguez-Sierra, J. (1984). EM Localization of SRIF-immunoreactivity in the medial nucleus of the trapezoid body. Anat. Rec. 208, 303.

Morley, B.J., Spangler, K. & Javel, E. (1984). Localization of somatostatin and choline acetyl­transferase in the interpeduncular nucleus of the developing cat. Soc. Neurosci. Abs. 10.

Morley, B.J., Spangler, K.M. & Javel, E. (1984). Localization of somatostatin immuno­reactivity in the interpeduncular nucleus of the developing cat. Presented at the Symposium on Somatostatin, Montreal, Canada.

Morley, B.J., Farley, G.R. & Javel, E. (1984). Putative neurotransmitter receptors in the central auditory system. Invited paper, Midw. Mtg., Assoc. Res. Otolarngol., Tampa, FL.

Spangler, K.M. & Morley, B.J. (1985). Somatostatin-immunoreactivity in the midbrain of the cat. Soc. Neurosci. Abs. 11, 803.

Garner, L.L. & Morley, B.J. (1986). a -bungarotoxin binding sites in selected hypothalamic nuclei of juvenile rats. Soc. Neurosci. Abs. 12, 308.

Kemp, G. & Morley, B.J. (1986). PC-12 cells do not have high affinity 3 H-acetylcholine binding sites. Soc. Neurosci. Abs. 12, 238.

Morley, B.J. (1987). Increases in the concentration of brain nicotinic receptors by dietary choline. 4th Mtg. Int'l Study Group, Pharmacol. of Memory Disorders Associated with Aging, Zurich, Switzerland.

Morley, B.J., Garner, L., Larsson, C., Fleck, D. & Murrin, L.C. (1987). Parameters affecting the up-regulation of brain nicotinic receptors by dietary choline. Soc. Neurosci. Abs. 13, 728.

Larsson, C., Fleck, D.L. & Morley, B.J. (1987). The regulation of brain a -bungarotoxin binding sites by nicotinic cholinergic agents. Soc. Neurosci. Abs. 13, 728.

Morley, B.J. & Ryan, T. (1989). A method for assessing the effects of nicotine on blood pressure and heart rate by telemetry. Presented at the 3rd Nebraska Symposium on Cancer and Smoking-related Disease.

Schneider, B.L., Morley, B.J. & Rodriguez-Sierra, J.F. (1989). Microscopic study of fetal hypo­thalamic tissue transplanted into the third ventricle of senescent female rats. Proc. 47th Ann. Mtg., Electron Microscopy Soc. Am., pp 950-951.

Schneider, B.L., Morley, B.J. & Rodriguez-Sierra, J.F. (1989). Studies of fetal hypothalamic tissue transplanted into the third ventricle of senescent female rats. Midw. Neurobiol. Assoc. St. Louis, MO.

Morley, B.J., Spangler, K.M., Schneider, B.L. & Javel, E. (1989). Degeneration of efferent terminals in the chinchilla cochlea by a cholinergic neurotoxin. Soc. Neurosci. Abs. 15, 211.

Rodriguez-Sierra, J.F., Burns, S.P., Warl, R.A., Schneider, B.L. & Morley, B.J. (1989). Infant rat exposure to aspartate and glutamate: Neuroendocrinopathies and structural analysis of brain damage. Int'l Mtg. on Amino Acids.

Roll, R., Morley, B.J. & Jones, T.A. (1989). A model to study the effects of chronically infused neuropharmacological agents on developing embryos. Soc. Neursci. Abs. 15, 1023.

Morley, B.J. (1990). Species variation in brain somatostatin. Presented at the Midwest Regional Conf. on Comp. Endocrinol., Am. Soc. Zool. Omaha, NE.

Smith, D., Petzel, J. & Morley, B.J. (1991). Synthesis, purification, and characterization of a putative endogenus ligand for the a -bungarotoxin protein thymopoietin. Soc. Neurosci. Abs. 17.

Weekly, J.M., Warr, W.B. & Morley, B.J. (1992). Distribution of olivocochlear neurons in the chinchilla. Soc. Neurosci Abs. 18.

Li, H.-S., Niedzielski, A., Beisel, K., Hiel, H., Wenthold, R.H. & Morley, B.J. (1993). Evidence for expression of a glutamate/aspartate transporter in rat cochlea. Soc. Neurosci Abs. 19, 1419.

Hiel, H., Warr, W.B. & Morley, B.J. (1993). Expression of sodium-dependent choline transport mRNA in auditory and vestibular nuclei. Soc. Neurosci Abs. 19, 536.

Chen, L., Kemp, G. & Morley, B.J. (1993). Evidence that a-bungarotoxin blocks increases in intracellular calcium in PC12 cells. Soc. Neurosci Abs. 19, 464.

Beisel, K.W., Kennedy, J.E., Hiel, H. & Morley, B.J. (1994). Construction and assessment of a rat outer hair cell unidirectional cDNA library. Presented at the Ann. Midwinter Res. Mtg, Assoc. Res. Otolaryngol.

Morley, B.J., Hiel, H. & Marks, M.J. (1994). Expression of nicotinic acetylcholine receptor genes in auditory brainstem nuclei. Presented at the Ann. Midwinter Res. Mtg, Assoc. Res. Otolaryngol.

Happe, H.K., Cerutis, D.R., Hiel, H., Marks, L.C. & Morley, B.J. (1995). Correspondence of a-bungarotoxin binding sites with a 7 and a 5 mRNA in rat brain. Paper presented at the ASPET meeting.

Hiel, H., Drescher, D., Elgoyhen, A. & Morley, B.J. (1995). nAChR subunits in the peripheral vestibular system. Presented at Molecular Biology of Hearing and Deafness, Washington, DC, October.

Li, H.-S., Hiel, H., Happe, H.K., Lindstrom, J., Wenthold, R.J. & Morley, B.J. (1995). Expression of nicotine cholinergic subunits in rat cochlea. Presented at Molecular Biology of Hearing and Deafness, Washington, DC, October 1995.

Morley, B.J. & Happe, H.K. (1995). An in situ hybridization study of mRNA expression for I 5 and I 6, putative nicotinic acetylcholine receptor subunits during postnatal development of the rat brain. Soc. Neurosci. Abs. 25, 1335.

Happe, H.K., Murrin, L.C. & Morley, B.J. (1995). Nicotinic Acetylcholine receptor autoradio­graphy and in situ hybridization of mRNA for a4 and a7 subunits: Expression during postnatal development of rat brain. Soc. Neurosci. Abs. 25, 11.

Hiel, H., Happe, H.K., Elgoyen, A.B. & Morley, B.J. (1996). Several subunits of the nicotinic receptor gene family are expressed in the rat peripheral vestibular system. Soc. Neurosci. Abs. 26, 1273.

Morley, B.J. & Happe, H.K. (1996). Development of the a 7 nAChR subunit and a -bungaro­toxin binding in the cochlea and auditory brain. Assoc. Res. Otolaryngol. Abs. 19, 88.

Morley, B.J., Li, H.-S., Hiel, H., Drescher, D.G. & Elgoyen, A.B. (1996). Identification of the subunits of the nicotinic cholinergic receptors in the rat cochlea using RT-PCR and in situ hybridization. Soc. Neurosci. Abs. 26, 1273.

Gupta, A.K., Chun, W.J., Sheikhali, S.A., Drescher, M.J., Morley, B.J. & Drescher, D.G. (1997). Coding sequence of an a 9-like nicotinic acetylcholine receptor subunit in a teleost hair cell sheet. Assoc. Res. Otolaryngol. Abs. 20, 215.

Kliment, M.L., Morley, B.J., Weekly, J.M. & Warr, W.B. (1997). Two types of lateral olivo­cochlear neurons in the chinchilla. Assoc. Res. Otolaryngol. Abs. 20, 162.

Simmons, D.D. & Morley, B.J. (1998). Embryonic expression of the a 9 nicotinic acetylcholine receptor subunit differs from postnatal expression in the rat cochlea. Assoc. Res. Otolaryngol. Abs. 21, 215.

Morley, B.J. (2000). Postnatal development of cholinergic receptors and synapses in the rat octopus cell region. Assoc. Res. Otolaryngol. Abstr. Presented at the 23rd Midwinter Research Meeting of the Association for Research in Otolaryngology, St. Petersburg Beach, FL, February.

Simmons, D.D. & Morley, B.J. (2001). Developmental expression of the a 10 nicotinic acetylcholine receptor subunit in the rat inner ear. Assoc. Res. Otolaryngol. Abst. 24, 98. (Abstract #348). Presented at the 24th Midwinter Research Meeting of the Association for Research in Otolaryngology, St. Petersburg Beach, FL, February.

Feng, F., Jia, S., He, D.Z.Z. & Morley, B.J. (2003). Outer hair cell functions in AChE knockout mice. Assoc. Res. Otolaryngol. Abst. 26, 106. (Abstract #417). Presented at the 26th Annual Midwinter Meeting of the Association for Research in Otolaryngology, Daytona Beach, FL, February.

Morley, B.J., Rodriguez-Sierra, J.F. & Roy, S. (2003). α7 Nicotinic acetylcholine receptor is obligatory for synchronous ovulatory cycles. Presented at the Nebraska Physiological Society Meeting, Lincoln, NE, April.

Morley, B.J., Nelson, N., Rodriguez-Sierra, J.F. & Roy, S.K. (2003). Ovulatory asynchrony in the female a 7 nCHR null mutant mouse. Presented at the Society for Neuroscience Meeting, New Orleans, LA, November.

 

Research Grants:

An Ultrastructural Study of the Effects of Chlorpromazine on Brainstem Neurons . Awarded Jan. 1972, Div. of Psychopharmacol. of the Am. Psychol. Assoc.

An Autoradiographic Investigation of the Incorporation of 3H-Uridine in Auditory Neurons Following Noise Exposure . Awarded Apr. 1973, Coe Res. Fund, Univ. of Maine, Orono (with R.M. Abelson).

Instructional Scientific Equipment Program in Biopsychology . Awarded Sep. 1976, NSF (with M.E. Hahn).

A Multi-User Grant for a Light Microscope . Awarded July 1978, NSF (Neurobiology) (with R.J. Bradley, J.F. Lorden & D. Sparks).

The Distribution and Origination of Cholinergic Terminals in the Mammalian Auditory System . UAB Faculty Research Grant, 1977.

The Effects of Cholinergic Agents on Catecholamine Release . UAB Faculty Research Grant, 1978.

Histochemical Identification of Nicotinic Acetylcholine Receptors in the CNS . Awarded Jan. 1979, NSF (Neurobiology).

Somatostatin in the Auditory System . Awarded Aug. 1982, NSF (Sensory Physiology); renewed August 1984 (Neurobiology).

Purification of Hair Cells from the Guinea Pig Cochlea . Awarded Dec. 1983, Deafness Research Foundation.

Communication Disorders in Children . Awarded April 1984, NIH-NINCDS. Program Project (R. Netsell, PI).

Drugs that Block the Regulation of Nicotinic Acetylcholine Receptors by Nicotine . Awarded July 1985, State of Nebraska; renewed July 1986.

Physiological and Behavioral Correlates of the Long-Term Administration of Nicotine . Awarded July 1987, State of Nebraska, renewed July 1988.

Studies of the Olivocochlear Lateral Efferents . Awarded April 1990, NIH, renewed April 1992 (1992-97) as Cholinergic Mechanisms in the Cochlea.

Efferent Neurotransmitter Systems in the Developing Cochlea . Awarded Oct. 1991, NIH, Project VI of Research and Training Center of Excellence (1991-95).

Nicotine-Mediated Sodium Flux in Primary Cultures . Awarded Feb. 1991, ADAMHA (1991-93).

The Development of Inhibition Within the Inferior Colliculus . Awarded January 1992, NIH-NIDCD (JoAnn McGee, PI).

Neurobiology of the Auditory System: Physiology of Isolated Nerve Terminals . Awarded April 1992 as Project V of Program Project Grant, NIH-NIDCD (A.P. Wangemann, PI).

Neurobiology of the Auditory System: Cholinergic Mechanisms at Efferent Synapses . Awarded April 1992 as Project VI of Program Project Grant, NIH-NIDCD; renewed February 1998-March 2003.

Neurobiology of the Auditory System: Electron Microscopy . Awarded April 1992 as Core D of Program Project Grant, NIH-NIDCD; renewed February 1998-March 2003.

Neurobiology of the Auditory System, Core A: Administration . Awarded February 1998, NIH-NIDCD (no-cost extension to 2004), W.B. Warr, PI.

Neurobiology of the Auditory System, Core C: Electron Microscopy . Awarded February 1998, NIH-NIDCD (no-cost extension to 2004).

Neurobiology of the Auditory System, Project III: Cholinergic Mechanisms at Efferent Synapses . Awarded February 2001, NIH-NIDCD (no-cost extension to 2004).

Gender Differences in Alpha7 Hypothalamic Nicotine Receptors . Awarded January 2003, NeHHS (2003-04).

A Mouse Model for Middle Age Infertility . Awarded February 2003, Olson Center for Women's Health at UNMC (2003-04).

Development and Characterization of an Alpha10 Knockout Mouse. Awarded January 2004, DRF (2004-07).

Development of an Alpha 10 Null Mutant Mouse . Awarded January 2004, NOHR (2004-05).

Characterization of nAChRs in ES, Progenitor, and Differentiated Hair Cells. Awarded January 2005, AHRF (2005-06).